Asthma

Location:
South Africa, Asthma NAD Level = 47 and Normal is 100+
Blood Requests Forms:
Ampath Labs

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Dr_Abram_Hoffer

  • Posted on 05/04/2010 08:55 am
This new work with NAD Therapy is very exciting and I think is right on target. It is indeed an energy-metabolic-deficiency (EMD) because in the absence of this coenzyme cycle almost all the reactions in the body run down... I congratulate Theo Verwey and his colleagues for this remarkable advance in using this concept and in using a simple test, the ratio of pyruvate to lactate as a diagnostic measure, to indicate the dose, duration of treatment etc.

NAD_Blood_Tests

  • Posted on 05/01/2010 12:07 pm
The ratio of lactate to pyruvate reflects the NAD/NADH ratio and is useful in distinguishing primary defects. Measured enzymatically in blood or CSF as an index of defects of glucose oxidation (fed state) or gluconeogenesis (fasted). (Center Inherited Disorders Energy Metabolism at CWR University School of Medicine, Cleveland, Ohio).

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Acid-base abnormalities in adults with acute asthma are highly variable. The major abnormalities have been attributed to changes in PaCO2 secondary to altered alveolar ventilation. Primary metabolic a… Read more

Blood gases and acid-base balance were measured in a group of patients in status asthmaticus. Simple or combined metabolic acidosis was found in 37.9% of the patients. In 25 of these, lactic acid (LA)… Read more

Hypokalemia and lactic acidosis developed following correction of respiratory acidosis in a 5-year-old child who presented with respiratory failure secondary to severe asthma and treated with theophyl… Read more

Lactic acidosis is a frequent laboratory finding in patients with severe exacerbations of asthma. The pathogenesis of lactic acidosis in asthma is not well understood, but it has been presumed, by som… Read more

Lactic acidosis is commonly associated with states of hypoxia and decreased tissue perfusion. Elevated lactic acid levels have also been observed in individuals who are not septic and who are normoten… Read more

BACKGROUND: Lactic acidosis is a well described phenomenon in adult patients with severe asthma. However, this entity is rarely reported in children with status asthmaticus.

OBJECTIVE: T… Read more

BACKGROUND: Lactic acidosis is a recognised event in adult patients with status asthmaticus, particularly in the setting of intensive care. However, it has been infrequently studied in patients attend… Read more

Asthmatics seeking emergency care for severe acute asthma may show metabolic acidosis. We sought to determine the frequency of metabolic acidosis in such patients and to assess the relative contributi… Read more

Twelve patients with severe asthma in whom lactic acidosis developed are presented. All had an arterial blood pH level lower than that expected for the measured partial pressure of arterial carbon dio… Read more

OBJECTIVE: To evaluate arterial lactate levels during treatment of acute severe asthma (ASA) and the prognostic value of arterial hyperlactatemia in ASA.

DESIGN: Prospective study.
Read more

Arterial and venous blood samples were obtained from 23 patients with acute asthma before they received systemic or intermittent positive-pressure breathing therapy.

Serum lactate, elect… Read more

On admission to intensive care units, the acid-base profile in acute severe asthma appears to be more diverse than previously. Especially a mixed or less frequently metabolic acidosis is eventually ob… Read more

The clinical features, arterial blood gases, and acid-base profile were examined in 229 consecutive episodes of acute asthma in 170 patients who required hospitalization.

A simple respir… Read more



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