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Autism

Location:
South Africa, Autism NAD Level = 70 and Normal is 100+
Blood Requests Forms:
Ampath Labs

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Dr_Abram_Hoffer

  • Posted on 05/04/2010 08:56 am
This new work with NAD Therapy is very exciting and I think is right on target. It is indeed an energy-metabolic-deficiency (EMD) because in the absence of this coenzyme cycle almost all the reactions in the body run down... I congratulate Theo Verwey and his colleagues for this remarkable advance in using this concept and in using a simple test, the ratio of pyruvate to lactate as a diagnostic measure, to indicate the dose, duration of treatment etc.

NAD_Blood_Tests

  • Posted on 05/01/2010 12:09 pm
The ratio of lactate to pyruvate reflects the NAD/NADH ratio and is useful in distinguishing primary defects. Measured enzymatically in blood or CSF as an index of defects of glucose oxidation (fed state) or gluconeogenesis (fasted). (Center Inherited Disorders Energy Metabolism at CWR University School of Medicine, Cleveland, Ohio).

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My NAD Articles Doccumenting NAD Relevancy

Metabolic biomarkers related to energy metabolism …

OBJECTIVES: Energy metabolism is usually manipulated in many neurodegenerative diseases. Autism is considered a definable systemic disorder resulting in a number of diverse factors that may affect the… Read more

Limbic circuitry in patients with autism spectrum …

OBJECTIVE: Cytoarchitectonic changes in the anterior cingulate cortex, hippocampus, subiculum, entorhinal cortex, amygdala, mammillary bodies, and septum were reported in a postmortem study of autism.… Read more

Clinical heterogeneity of the autistic syndrome: a…

Sixty families ascertained through a single proband, has helped to better define infantile autism as a heterogeneous group of disorders. Forty four patients showed a characteristic facio- auricular dy… Read more

The serotonin system in autism.

The serotonin system has been implicated as a factor in some cases of autism since the finding in 1961 of elevated serotonin (5-hydroxytryptamine) levels in the blood of patients with autism. This has… Read more

Relative carnitine deficiency in autism.

A random retrospective chart review was conducted to document serum carnitine levels on 100 children with autism. Concurrently drawn serum pyruvate, lactate, ammonia, and alanine levels were also avai… Read more

Mitochondrial dysfunction in autistic patients wit…

Two autistic children with a chromosome 15q11-q13 inverted duplication are presented. Both had uneventful perinatal courses, normal electroencephalogram and magnetic resonance imaging scans, moderate … Read more

Mitochondrial dysfunction in autism spectrum disor…

A minority of cases of autism has been associated with several different organic conditions, including bioenergetic metabolism deficiency.

In a population-based study, we screened associ… Read more

Hyperserotonemia and amine metabolites in autistic…

Mean whole blood serotonin (5-HT) levels were elevated in groups of autistic and severely retarded children. Eight of 27 (30%) individual autistic children, 13 of 25 (52%) severely retarded children, … Read more

Effects of tryptophan depletion in drug-free adult…

BACKGROUND: The primary objective of this study was to investigate the behavioral and biochemical responses to acute tryptophan depletion in drug-free adult patients with autistic disorder.
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Autism and lactic acidosis.

Four patients are described who have two coexistent syndromes: the behavioral syndrome of autism and the biochemical syndrome of lactic acidosis. One of the four patients also had hyperuricemia and hy… Read more

A frequent association of lactic acidosis and carn…

Autism is a developmental disorder characterized by disturbance in language, perception and socialization.

A variety of biochemical, anatomical and neuroradiographical studies imply a di… Read more



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