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MalaikaNAD
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Movie Trailers Illustrating My NAD Deficiencies
My NAD Articles Doccumenting NAD Relevancy
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Pharmacokinetics of the dietary supplement creatin…
Creatine is a nonessential dietary component that, when supplemented in the diet, has shown physiological benefits in athletes, in animal-based models of disease and in patients with various muscle, n… Read more
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Creatine: endogenous metabolite, dietary, and ther…
Creatine and phosphocreatine serve not only as an intracellular buffer for adenosine triphosphate, but also as an energy shuttle for the movement of high-energy phosphates from mitochondrial sites of … Read more
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A creatine-protein-carbohydrate supplement enhance…
PURPOSE: Studies attributing gains in strength and lean body mass (LBM) to creatine monohydrate (CrM) during resistance exercise (RE) training have not assessed these changes alongside cellular and su… Read more
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Fatigue and changes of ATP, creatine phosphate, an…
Fatigue during the 400-m sprint was studied by measuring muscle ATP, creatine phosphate (CP), lactate (M-La), and blood lactate (B-La) in six male runners before and after four experimental sprints (1… Read more
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Creatine-enhanced diet alters levels of lactate an…
Free fatty acids (FFA) and lactic acid are markers of secondary cellular injury following traumatic brain injury (TBI). We previously showed that animals fed a creatine (Cr)-enriched diet are afforded… Read more
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Treatment of Kearns-Sayre syndrome with coenzyme Q…
We studied the metabolism of coenzyme Q10 (CoQ) and the effects of CoQ therapy in five patients with Kearns-Sayre syndrome (KSS). Although the mitochondrial fraction was increased in muscles from KSS … Read more
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A case of motor and sensory neuropathy with elevat…
A 16-year-old high school male student was admitted to our hospital with complaints of difficulty in walking and muscle atrophy of the lower legs. He noticed his gait disturbance when he was about 12 … Read more
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Effects of coenzyme Q10 administration on pulmonar…
Serum coenzyme Q10 (CoQ10) levels were measured at rest and during incremental exercise in 21 patients with chronic obstructive pulmonary disease (COPD) and 9 patients with idiopathic pulmonary fibros… Read more
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Energy metabolism defects in Huntington's disease …
We investigated whether the Huntington's disease (HD) gene mutation may produce either primary or secondary effects on energy metabolism. 31P magnetic resonance spectroscopy demonstrated a significant… Read more
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The effects of coenzyme Q10 treatment on maternall…
The characteristic clinical features of diabetes mellitus with mitochondrial DNA (mtDNA) 3243(A-G) mutation are progressive insulin secretory defect, neurosensory deafness and maternal inheritance, re… Read more
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Metabolic changes in patients with mitochondrial m…
We used a standardized bicycle ergometry protocol with a stepwise increasing workload (30-100 W) to evaluate various metabolic factors for the diagnosis and metabolic monitoring of mitochondrial encep… Read more
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Coenzyme Q10 administration and its potential for …
Coenzyme Q10 (CoQ10) is an essential cofactor of the electron transport chain as well as an important antioxidant. Previous studies have suggested that it may exert therapeutic effects in patients wit… Read more
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Coenzyme Q10, exercise lactate and CTG trinucleoti…
Steinert's myotonic dystrophy (DM) is a genetic autosomal dominant disease and the most frequent muscular dystrophy in adulthood. Although causative mutation is recognized as a CTG trinucleotide expan… Read more
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Cytochemical activity of mitochondrial enzymes in …
Using cytochemical computerized morphometric method, activity of the key enzymes of energetic metabolism (succinate dehydrogenase, alpha-glycerophosphate dehydrogenase, malate dehydrogenase, glutamate… Read more
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Coenzyme Q10 deficiency and isolated myopathy.
Three unrelated, sporadic patients with muscle coenzyme Q10 (CoQ10) deficiency presented at 32, 29, and 6 years of age with proximal muscle weakness and elevated serum creatine kinase (CK) and lactate… Read more
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The mitochondrial cocktail: rationale for combined…
Mitochondrial cytopathies ultimately lead to a reduction in aerobic energy transduction, depletion of alternative energy stores, increased oxidative stress, apoptosis and necrosis.
Speci… Read more |
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The role of guaifenesin in the treatment of sinona…
Inflammatory sinonasal disease is a common problem in patients infected with the human immunodeficiency virus (HIV). Although some patients present with acute or chronic sinusitis, many describe persi… Read more
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Successful pregnancy despite advanced age and elev…
PURPOSE: To determine if a woman over age 45 with elevated serum follicle stimulating hormone (FSH) levels in the early follicular phase could still successfully conceive.
METHODS: Femal… Read more |
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Guaifenesin as a treatment for primary dysmenorrhe…
BACKGROUND: Dysmenorrhea is highly prevalent and causes much work loss and discomfort. A treatment with a new mechanism of action could benefit women of menstruating age. A study was undertaken to ass… Read more
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Self-reported medication and herb/supplement use b…
METHODS: Using a telephone survey of 434 women who self-reported having and 198 women, who denied having fibromyalgia (FM) (aged 18-80 years), we compared women on self-reported number, major types, a… Read more
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