This retrospective study interprets the results of 370 evaluations of the lactate level of joint fluid. 5 groups were established: joint fluid from cases of mechanical (114) and microcrystalline (67) joint diseases, from inflammatory arthritis (149) and from septic arthritis (40).
There was a significant difference between the lactate level in fluid from septic joints and that in the…
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1H-nuclear magnetic resonance studies of human synovial fluid in arthritic disea…
1. A 1H-n.m.r. method was used to measure concentrations of valine, alanine, lactate, acetate, hyaluronan and lipids in synovial fluid obtained, during the normal course of examination from the knee joints of patients attending rheumatology and orthopaedic clinics. Fluid was available from 16 patients with osteoarthritis, 18 patients with rheumatoid arthritis, four patients with meniscal tear and …
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Synovial fluid interleukin-8 and neutrophil function in rheumatoid arthritis and…
The relationships between synovial fluid (SF) interleukin-8 (IL-8) and neutrophil turnover as measured by cytidine deaminase (CD), and SF metabolites were studied in 28 patients, 16 with rheumatoid arthritis (RA; median age and disease duration 62 and 14 yr, respectively) and 12 with seronegative polyarthritis (SNP; median age and disease duration 32 and 5 yr, respectively).
Knee SF … |
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The purine nucleotide content of lymphocytes from patients with rheumatoid arthr…
A procedure has been described for the preparation of T and non-T lymphocyte populations. The purine nucleotide contents were analyzed by high-performance liquid chromatography. In healthy subjects the pattern was shown to be different in the two cell populations.
In patients with rheumatoid arthritis the findings as compared with the healthy subjects were as follows; in T cells the … |
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Synovial milieu in gouty arthritis.
The synovial milieu in uric arthritis is characterized with the help of own findings of examinations and data in literature. Apart from the mean values of cytological and biochemical findings of the synovia the changes under therapy are described on the basis of individual examples. The formation of monosodium urate crystals seems to be the starting point of the inflammatory joint process in gout.…
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Synovial fluid lactate levels in septic and non-septic arthritides.
Lactate concentration was studied in 383 synovial fluid specimens from patients with various arthritides. The highest concentrations of lactate occurred in non-gonococcal septic synovial fluids. High values were recorded in seropositive rheumatoid arthritis and crystal-induced arthritides, medium values in synovial fluids from seronegative rheumatoid arthritis, seronegative spondylarthritides, gon…
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Synovial fluid lactate and the diagnosis of septic arthritis.
To assess the value of synovial fluid lactate estimation in the diagnosis of septic arthritis, 238 specimens received for routine culture and 75 reference samples were examined using a rapid enzyme technique. Samples were collected without special treatment and the effect of delay in transport to the laboratory investigated.
Raised levels were found in all cases of untreated septic a… |
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Lactate UV-system: a rapid method for diagnosis of septic arthritis.
The concentration of lactic acid in synovial fluid was estimated in 43 specimens from patients with an acute monoarthritis by a simple enzyme method. In 9 patients with 10 episodes of septic arthritis concentrations of synovial fluid lactic acid were significantly higher (mean 10.8 mmol/l) than in 33 patients with nonseptic effusions (mean 3.1 mmol/l).
With this method concentrations… |
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Lactate levels were highest in septic arthritis.
Synovial fluid from 16 normal subjects was compared with that from 149 patients with a variety of rheumatic disorders. Normal fluid had fewer cells and a lower content of beta-glucuronidase than osteoarthritic samples.
Particles, including occasional birefringent crystals, were seen in normal fluids as well as pathological samples. Alizarin red staining particles (presumed to contain… |
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