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I became interested in the pyridine nucleotide cycle, NAD<-->NADH in the early 1950's after we had demonstrated that vitamin B3, one of the main precursors of this system tripled the recovery rates of acute schizophrenic patients compared to a placebo. The pure vitamins are the natural precursors in the body of the pyridine nucleotide cycle. Either niacinamide or niacin yielded the same bene…

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