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Jack Nicholson and Morgan Freeman star as two terminally ill cancer patients who decide to break out of the hospital and live their last days to the fullest in director Rob Reiner's seriocomic road movie. Edward Cole (Nicholson) is a corporate billionaire who is currently sharing a hospital room with blue-collar mechanic Carter Chambers (Freeman). Though initially the pair seems to have nothing in common, conversation gradually reveals that both men have a long list of goals they wish to accomplish before they kick the bucket
This article summarizes data from experimental and clinical oncology which are indicative of a pivotal role of tumor carbohydrate metabolism in malignant behavior and outcome of treatment.
It is postulated that a decrease in nicotinamide adenine dinucleotide (NAD) concentration has a primary association with carcinogenesis. The following observations are presented as evidence: Read more
Studies presented here show that cellular NAD, which we hypothesize to be the relevant biomarker of niacin status, is significantly lower in humans than in the commonly studied animal models of carcin… Read more
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My NAD Articles Doccumenting NAD Relevancy
Lactate and redox status in malignant tumors
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An association of carcinogenesis and decrease of c…
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Mapping the role of NAD metabolism in prevention a…