1. Cataract is the single major cause of blindness worldwide; however, the reasons for the development of this condition remain unknown. It has been suggested that the essential amino acid tryptophan may be implicated in the aetiology but definitive evidence has been lacking.
2. The serum levels of tryptophan and seven of its metabolites have been measured in both cataract patients a…
 |
 |
Cataract and metabolic disease.
In addition to the already recognized metabolic diseases which have been associated with cataract formation, e.g. galactosaemia, galactokinase deficiency, Lowe's syndrome and diabetes, several other disorders can also lead to the development of cataracts.
They are sorbitol dehydrogenase deficiency, uridine diphosphate galactose-4-epimerase deficiency, marginal maternal transferase an… |
 |
Cataractous lenses had lower levels of all nucleotides than the normal lenses
The levels of NAD+, NADH, NADP+ and NADPH have been determined in each cortex and nucleus of about 80 normal and cataractous human lenses and in a small number of calf, rabbit and rat lenses.
Cataractous lenses had lower levels of all nucleotides than the normal lenses but no progressive decreases were associated with the development of nuclear colour, or with cortical, diabetic, tra… |
| Alkogen Products - Practitioners call 079 102 9157 | Nutrimalaika - General Public call 074 201 6334 |
 |
 |
