Macromolecular LD (lactate dehydrogenase, EC 1.1.1.27) was present in the serum of a patient suffering from idiopathic fibrosis of the lung and presenting signs of autoimmune disease.
By using gel filtration and affinity chromatography techniques, the vast majority of the patient\'s serum LD activity was shown to consist of LD-IgG complexes, which dissociated in the presence of added…
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Circulating IgG-LD complex, dissociable by addition of NAD+.
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