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Derailed starts as what seems to be the setup for a modern Fatal Attraction. Clive Owen plays Charles Schine, a man with a moderately happy marriage that’s been strained due to his daughter’s illness (type-I diabetes). By chance, one day he meets Lucinda (Jennifer Aniston), a beautiful and intelligent woman, and the two quickly discover how much they have in common.
Diabetic retinopathy is thought to result from chronic changes in the metabolic pathways of the retina. Hyperglycemia leads to increased intracellular glucose concentrations, alterations in glucose de… Read more
AIMS/HYPOTHESIS: Studies of the role of sorbitol dehydrogenase in nerve functional deficits induced by diabetes reported contradictory results. We evaluated whether sorbitol dehydrogenase inhibition r… Read more
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My NAD Articles Doccumenting NAD Relevancy
Changes in the redox state in the retina and brain…
Evaluation of a sorbitol dehydrogenase inhibitor o…
Elevated glucose levels increase retinal glycolysi…
METHODS. Freshly isolated retinas from normal male Sprague-Dawley rats were i… Read more