Homocysteine is a sulphurated amino acid which, at high plasma concentrations, predisposes to thrombosis and induces focal arteriosclerosis.
These characteristics have been established both in patients with homocystinuria, a genetic disease in which homocysteine accumulates in the blood, and in animals submitted to intravenous infusions of this amino acid.
Many recent p…
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Homocysteine, a risk factor of atherosclerosis.
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Large decreases in cellular NAD+ occurred in response to homocysteine induced to…
In response to homocysteine induced toxicity in human umbilical vein endothelial cells, minimal changes in the concentration of cellular protein thiols but substantial changes in the concentration of intracellular soluble thiols were observed. The latter correlated closely with changes in cellular glutathione levels.
No correlation existed between cellular glutathione levels and cell… |
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