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The dangers of fructose-sorbitol infusions

A report is given on 2 patients with postoperative liver and kidney insufficiency who showed a hereditary fructose intolerance (HFI) after the infusion of fructose and sorbitol. The pathophysiological and clinical signs of this rare disease are described.

Since irreversible organ damage occurs already after the infusion of more than 30 to 40 grams fructose or sorbitol, every therapy is questionable. Therefore, prophylactic measures are important in infusion therapy.

Particularly in emergency patients and during the preanaesthetic investigation of patients, HFI must be taken into account in adults.

About the Authors

Karrenberg R, Stober HD. (1990) The dangers of fructose-sorbitol infusions. Anaesthesiol Reanim. 1990;15(3):181-7. Abteilung fur Anasthesiologie und Intensivtherapie, St. Hedwig-Krankenhaus, Berlin.

Comments

Dr_Abram_Hoffer

  • Posted on 05/13/2010 02:29 am
This new work with NAD Therapy is very exciting and I think is right on target. It is indeed an energy-metabolic-deficiency (EMD) because in the absence of this coenzyme cycle almost all the reactions in the body run down... I congratulate Theo Verwey and his colleagues for this remarkable advance in using this concept and in using a simple test, the ratio of pyruvate to lactate as a diagnostic measure, to indicate the dose, duration of treatment etc.

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